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The Art and Science of Dermal Formulation Development

Drugs and the Pharmaceutical Sciences

Format: Hardback
Publisher: Taylor & Francis Ltd, London, United Kingdom
Imprint: CRC Press
Published: 11th Mar 2019
Dimensions: w 161mm h 240mm d 20mm
Weight: 510g
ISBN-10: 1138064920
ISBN-13: 9781138064928
Barcode No: 9781138064928
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Synopsis
The Art and Science of Dermal Formulation Development is a comprehensive guide to the theory and practice of transdermal and topical formulation development, covering preclinical studies, evaluation, and regulatory approval. It enables the reader to understand the opportunities and challenges in developing products and how risks can be mitigated. Over the last 25 years, expertise in this area has declined whilst drug delivery systems for other administration routes have developed significantly. The advantages offered by transdermal and topical drug delivery remain compelling for sectors including the pharmaceutical industry, personal care, and cosmetics. This text addresses the dearth of expertise and discusses how skin can be a route of delivery and the processes in formulation development, but how such an application is very different to that used for oral, IV, and other administration routes. Key Features: Presents a practical guide for both industry and academia Focuses on and draws together the fundamental principles behind transdermal and topical drug delivery Illustrates the practicalities of formulation design using key case studies Gives an understanding of the skin as a route of delivery and how formulation development for such application differs from that for other administration routes

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