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Neurosteroids and the Nervous System

SpringerBriefs in Neuroscience

By (author) Steven R. King
Format: Paperback / softback
Publisher: Springer-Verlag New York Inc., New York, NY, United States
Published: 9th Nov 2012
Dimensions: w 156mm h 234mm d 7mm
Weight: 197g
ISBN-10: 1461455588
ISBN-13: 9781461455585
Barcode No: 9781461455585
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Synopsis
While steroids from the periphery have profound effects on the nervous system, the nervous system also produces its own steroids de novo ("neurosteroids"). The physiological importance of neurosteroids is beginning to be understood. These steroids potentially have roles in sedative/hypnotic behavior, anxiety, learning, and memory. At the cellular level, neurosteroids affect neuronal excitability, synaptic plasticity and cell proliferation and survival. Early findings hold promise for future strategies to treat specific psychologicalconditions and neurological diseases. This Brief will focus on the current state of understanding of brainderived neurosteroids.

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