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Applied Surrogate Endpoint Evaluation Methods with SAS and R

Chapman & Hall/CRC Biostatistics Series

Format: Hardback
Publisher: Taylor & Francis Inc, United States
Imprint: Chapman & Hall/CRC
Published: 8th Dec 2016
Dimensions: w 156mm h 232mm d 29mm
Weight: 755g
ISBN-10: 1482249367
ISBN-13: 9781482249361
Barcode No: 9781482249361
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Synopsis
An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment's efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.

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"This is a timely text. The number of published studies using surrogate endpoints has increased dramatically since the early work of the 1980s; however, there is a dearth of available texts or software on this topic. Anyone with an interest in surrogate endpoint evaluation would benefit from this text."
~Statistics in Medicine