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Chaperones

Methods and Protocols. Methods in Molecular Biology 1709

Format: Hardback
Publisher: Humana Press Inc., Totowa, NJ, United States
Published: 26th Nov 2017
Dimensions: w 178mm h 254mm d 25mm
Weight: 1025g
ISBN-10: 1493974769
ISBN-13: 9781493974764
Barcode No: 9781493974764
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Synopsis
This volume is a compilation of laboratory protocols and methodology required for the study of molecular chaperones and the cellular stress response. Chapters detail stress response in Hsf1, Hsf2 and Hsf4 knockout mice, mapping HSP interaction networks, the LUminescence-based Mammalian IntERactome (LUMIER), Hsp70 biology, protein folding activity of Hsp90, cytotoxicity of HSP inhibitors, computational approaches for modeling allosteric Hsp90 interactions, HSPs in immunity and vaccine development , and biologies of Hsp70 and Hsp90. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Chaperones: Methods and Protocols aims to ensure successful results in the further study of this vital field.

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