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Cancer Driver Genes

Methods and Protocols. Methods in Molecular Biology 1907

Edited by Timothy K. Starr
Format: Hardback
Publisher: Humana Press Inc., Totowa, NJ, United States
Published: 13th Dec 2018
Dimensions: w 178mm h 254mm d 14mm
Weight: 616g
ISBN-10: 1493989669
ISBN-13: 9781493989669
Barcode No: 9781493989669
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Synopsis
This book presents protocols for identification of genetic drivers of cancer. Chapters guide readers through a brief history of cancer gene discovery, in silico approaches, in vitro approaches, and in vivo approaches using forward genetic screens in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Driver Genes: Methods and Protocols aims to provide protocols that will be used and adapted by cancer researchers to expand the knowledge base of molecular mechanisms contributing to initiation, progression, and metastasis of cancer.

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