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Erythrocytes of the Rhesus and Cynomolgus Monkeys

Format: Hardback
Publisher: Taylor & Francis Inc, Bosa Roca, United States
Imprint: CRC Press Inc
Published: 22nd Dec 2015
Dimensions: w 154mm h 235mm d 19mm
Weight: 534g
ISBN-10: 149873359X
ISBN-13: 9781498733595
Barcode No: 9781498733595
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Synopsis
Erythrocytes of the Rhesus and Cynomolgus Monkeys addresses the morphologic, quantitative, and generative aspects of the erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus monkey Macaca fascicularis (long-tailed macaque, crab-eating monkey). These two species are the most commonly selected nonhuman primates for basic science and clinical medical investigations. The hemopoietic cells of man and the rhesus monkey display an intimate homogeneity. Their functional activities are close and at times identical. The cynomolgus monkey was enlisted in biomedical studies at a time when rhesus monkeys were not available in sufficient quantities. It has gained increased use in the Far East and in the Western world. It is, for example, employed in the current development of a vaccine against the deadly Ebola virus. The authors of the book discuss the erythropoietic profiles of normal and abnormal macaques of both sexes and of all age groups as investigated with contemporary electronic methodologies. They cover the role of stress as it is perceived by the monkey and how it impacts erythrocellular values, and how to train the monkey to be a cooperative, unperturbed subject for hematologic study. Additional topics include the role of medication in deriving normal physiologic erythrocellular data, the development of the precursors of the erythrocyte (normoblasts), the morphologic analysis of the megaloblastic series of abnormal erythroid cells, the analysis of erythropoiesis in bone marrow, the relationship of the simian immunodeficiency virus and erythropoiesis, erythrocyte life span, and parasitic invasion of the red cell.

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"Erythrocytes of the Rhesus and Cynomolgus Monkeys is a text that addresses the morphologic, quantitative, and generative aspects of erythrocytes of the rhesus monkey Macaca mulatta and the cynomolgus monkey Macaca fascicularis (long-tailed macaque, crab-eating monkey). These two species are the most commonly selected nonhuman primates for biomedical scientific investigations. ... The book includes many useful tables, drawings and images to illustrate important concepts in erythrocyte science. It also includes a useful meta-analysis of normative ranges in tables toward the end of the book. These tables are organized by species and include the references from which the erythrocyte data ranges are extracted. ... Overall, the text does provide a valuable reference and resource for non-human primate scientists and veterinarians. I would recommend this book especially for investigators who study erythrocyte biology and diseases of red blood cells." Dr. Diana Scorpio, DVM, MPH, DACLAM (Vaccine Research Center, National Institutes of Health, Bethesda MD) in Laboratory Animal Practitioner