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Sensor Technology in Neuroscience
Detection Science Volume 1
Synopsis
Biosensor technology has rapidly expanded into a wide variety of applications in the last few years. Such fields include clinical diagnostics, environmental chemistry, drug discovery and pathogen detection, to name but a few. The structure of these sensors is based on the intimate combination of a biological entity with a transducer capable of generating an electrical signal to provide information on the biological system being studied. Until now there has been a limited treatment of the study of whole cells (as a biological component) due to the difficulty in connecting transducers to cell populations. This book focuses on several aspects of neural behaviour both in vitro and in vivo, and for the first time, the detection of populations of neurons (rather than single cells) will be presented. The fundamental behaviour and characterization of neurons on various substrates, using a variety of electronic devices such as transistors and microelectrode arrays will be discussed. Future perspectives discussed in the book include artificial intelligence using biological neural networks and nanoneuromedicine. The authors have considerable experience in biosensor technology, and have pioneered the study of neural populations using biosensors in collaboration with neurophysiologists and neuroendrocrinologists. This book will be invaluable to university neuroscience and analytical chemistry departments and students, academics and physicians will benefit from its accessible style and format.
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What Reviewers Are Saying
The book is very well organized
Overall, the book has been a very interesting read. The author has managed to explain and demystify the complex topic of neuroscience research using very clear and simple language. The best part about the book is that it does not require specific background knowledge of the topic, making it easy for readers of different disciplines to understand the operating principles and key design criteria for a neuro sensor. I would highly recommend the book for scientists that wish to start their research in the field of neuroscience, or for experienced neuroscientists that wish to explore alternative mechanisms for their sensors. -- Dr. Anis N. Nordin * Biosensors & Bioelectronics * "The authors succeed...by providing concise explanations of complex physical and biological concepts, including Plasmon resonance and the origins of Alzheimer's disease...This book contains an up-to-date overview of sensor technology used in neuroscience. The modular structure of the book makes it easy to review topics independently of each other. The authors explain both the physical basis of sensor design and the biological origins of the generated signal....The book can be used by scientists and engineers in related subjects as a comprehensive source of insight into sensor technology in neuroscience." -- Pavel Takmakov, Division of Chemistry and Material Science, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Food and Drug Administration * Analytical and Bioanalytical Chemistry (2014) 406:5257-5258 *