Each year, ONS receives thousands of clinical inquiries from oncology nurses and other healthcare professionals about many cancer care-related topics. The ONS clinical staff comprises advanced practice oncology nurses who reply to each inquiry, providing evidence-based answers, recommendations, and resources to guide practice. Careful analysis of the questions submitted to ONS reveals that the vast majority address safety and practice issues for chemotherapy and biotherapy administration, venous access devices, and staffing/policy development. The second edition of ONS Clinical Top 20: Answers to Your Questions About Chemotherapy and Biotherapy Administration addresses the most common questions submitted to ONS, including those relating to safety and practice issues for chemotherapy/biotherapy administration, venous access devices, and staffing/policy development. Designed to assist you in identifying problems and finding and proposing solutions, this second edition is a compilation of updated evidence-based answers to your most commonly asked questions.