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Alpha-1 Antitrypsin

Role in Health and Disease. Respiratory Medicine

Format: Hardback
Publisher: Birkhauser Verlag AG, Basel, Switzerland
Published: 6th Jan 2016
Dimensions: w 155mm h 235mm d 15mm
Weight: 4359g
ISBN-10: 331923448X
ISBN-13: 9783319234489
Barcode No: 9783319234489
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Synopsis
This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of rare disorders linked to alpha-1 antitrypsin deficiency and the role of healthcare organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.

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