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Resistance to Tyrosine Kinase Inhibitors

Resistance to Targeted Anti-Cancer Therapeutics

Edited by Daniele Focosi
Format: Hardback
Publisher: Springer International Publishing AG, Cham, Switzerland
Published: 14th Nov 2016
Dimensions: w 156mm h 234mm d 13mm
Weight: 465g
ISBN-10: 3319460900
ISBN-13: 9783319460901
Barcode No: 9783319460901
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Synopsis
The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.

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