🎉   Please check out our new website over at books-etc.com.

Seller
Your price
£36.14
RRP: £44.99
Save £8.85 (20%)
Printed on Demand
Dispatched within 14-21 working days.

Interleukin 12: Antitumor Activity and Immunotherapeutic Potential in Oncology

SpringerBriefs in Immunology

Contributions by Marek Jakobisiak
Format: Paperback / softback
Publisher: Springer International Publishing AG, Cham, Switzerland
Published: 6th Oct 2016
Dimensions: w 156mm h 234mm d 4mm
Weight: 132g
ISBN-10: 3319469053
ISBN-13: 9783319469058
Barcode No: 9783319469058
Trade or Institutional customer? Contact us about large order quotes.
Synopsis
This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies).

New & Used

Seller Information Condition Price
-New£36.14
+ FREE UK P & P

What Reviewers Are Saying

Be the first to review this item. Submit your review now