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Alternative Splicing and Disease

Progress in Molecular and Subcellular Biology 44

Edited by Philippe Jeanteur
Format: Paperback / softback
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, Berlin, Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Published: 30th Nov 2010
Dimensions: w 156mm h 234mm d 15mm
Weight: 386g
ISBN-10: 3642070817
ISBN-13: 9783642070815
Barcode No: 9783642070815
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Synopsis
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medical implications, i.e. diseases, caused by alternative splicing. Alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences. The book also outlines possible targets for therapy.

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