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Experimental Metastasis: Modeling and Analysis

Edited by Anastasia Malek
Format: Paperback / softback
Publisher: Springer, Dordrecht, Netherlands
Published: 17th Sep 2016
Dimensions: w 156mm h 234mm d 12mm
Weight: 316g
ISBN-10: 9402402748
ISBN-13: 9789402402742
Barcode No: 9789402402742
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Synopsis
Metastatic dissemination of cancer is a main cause of cancer related deaths, therefore biological mechanisms implicated in metastatic process presents an essential object of cancer research. This research requires creation and utilization of adequate laboratory models. The book describes main approaches to model processes of metastatic cancer dissemination and metastases development. The book is structured in according with various metastatic pathways reflecting molecular specificity of metastatic process as well as anatomical specificity of aria of dissemination. Each chapter is introduced by short discussion of clinical aspects of certain metastatic pathway. Especial attention is paid for methods of visualization, quantification and analysis of the modeled metastases. Additional chapter is devoted to methods of mathematic modeling of tumor spread. The data presented in the book may be helpful for cancer researchers and oncologists.

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