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Yeast Cell Surface Engineering

Biological Mechanisms and Practical Applications

Edited by Mitsuyoshi Ueda
Format: Hardback
Publisher: Springer Verlag, Singapore, Singapore, Singapore
Published: 9th May 2019
Dimensions: w 156mm h 234mm d 13mm
Weight: 455g
ISBN-10: 9811358672
ISBN-13: 9789811358678
Barcode No: 9789811358678
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Synopsis
This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.

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