This volume explores the latest experimental and clinical research on brain plasticity. Leading international investigators examine the brain capacity for functional recovery after various types of injury, including traumatic or ischaemic brain injury and such demyelinating diseases as multiple sclerosis. The first section of the book examines neuronal repair mechanisms, including molecular factors, regrowth and sprouting. The second section reviews experimental data on functional restoration in different brain systems. The third section goes on to present recent findings on plasticity in the human brain, including plasticity of the vestibular system and the motor cortex, recovery from subcortical stroke, recovery of language after brain damage and the flexibility in the structure of information processing. The final section, on therapeutic approaches, includes chapters on the role of polypeptide growth factors in recovery from strokes; noradrenergic enhancement of physical therapy for stroke or trauma patients; and late recovery of motor functions.