Acting as an up-to-date source on metabolic processes during exercise, this book provides a complete review of the literature, and synthesizes the research on the topic. The text examines in depth the mobilization and utilization of substrates during physical activity, focusing on skeletal muscle. It also discusses the important roles of liver and adipose tissue in exercise metabolism. The first five chapters of the boook summarize metabolic response to exercise. The sixth and seventh chapters consider several current issues: metabolic shifts in endurance-trained individuals, and how metabolism induces fatigue, mechanical manifestations of fatigue, specific fatigue sites, and myofibrillar determinants of fatigue. Summaries at the end of each chapter condense the information and facilitate understanding.