This practical review of the general principles of and the specific indications for spinal cord stimulation presents up-to-date applications of this technology, including the management of tractable pain and applications outside the nervous system. The text covers patient selection and preimplantation evaluation, instrumentation, standard implantation techniques, perioperative care and initial programming as well as long-term follow-up and reprogramming. It examines the role of spinal cord stimulation in postlaminectomy syndrome, peripheral nerve injury and deafferentation pain, sympathetically mediated pain syndromes, peripheral vascular disease, spinal cord injury and motor disorders. Implantation techniques for percutaneous and laminotomy electrodes, electrode arrays, and multiple stimulators are systematically described and illustrated. Also addressed are common perioperative complications and their management, including delayed failure of spinal cord stimulation.