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The Nuts and Bolts of Life

By (author) Paul Heiney
Format: Hardback
Publisher: The History Press Ltd, Stroud, United Kingdom
Imprint: Sutton Publishing Ltd
Published: 1st Oct 2007
Dimensions: w 138mm h 216mm
ISBN-10: 0750928948
ISBN-13: 9780750928946
Barcode No: 9780750928946
Paul Heiney describes here how one man - defiant, ingenious and stubborn - worked under impossible conditions in a country under the merciless occupation of Nazism to solve the problem of kidney failure and to change the course of human history. That man was Willem Kolff, aged 88 at the time of this book's publication. Tormented by the unnecessary deaths from kidney failure, Kolff determined to use mechanical ingenuity to purify blood. Working with sausage skins and an improbable collection of parts scavenged from factories under the nose of the German occupying forces, he completed the first kidney machine in 1944. It was a milestone in medical history: it is estimated that as many as half a million people in the world today owe their lives to this single invention. Kolff continued his career with pioneering work on the artificial heart. This book, written with Dr Kolff's closest co-operation and family records, celebrates that central story of courage and obsession, and its journey from the old, war-torn world to the new. It explains the science in accessible terms, and explores some of the human stories which developed along the way: the lives prolonged, new chances given to patients as the age of transplantation dawned, and the relationship between medical scientists and the army of technicians who make possible that strangest of 20th-century treatments - the circulation and purifying of the blood outside the human body.

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One of the great untold stories of medical endeavour: how Willem Kolff, now 88, solved the problem of kidney failure and changed the course of human history. Written by writer and broadcaster Paul Heiney with the cooperation of Dr Kolff and family records.