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Vaccinia Virus and Poxvirology

Methods and Protocols

By (author) Stuart N. Isaacs
Edited by Stuart N. Isaacs
Format: Online resource
Publisher: Humana Press Inc., Totowa, NJ, United States
Published: 30th Apr 2004
ISBN-10: 1592597890
ISBN-13: 9781592597895
Barcode No: 9781592597895
This volume provides a comprehensive source of protocols for working with poxviruses. Poxviruses are an important topic because of smallpox bioterrorism and the need to develop anti-poxvirus therapeutics and safer smallpox vaccines. The protocols cover everything from the construction, characterization, and use of recombinant viruses to methods for studying the poxvirus gene transcription and DNA replication, and poxvirus bioinformatics. Also covered are protocols involving the study of immune responses to poxvirus, which is a critical issue given their role in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer, thus making this book useful for all researchers of poxvirus.

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