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Target Identification and Validation in Drug Discovery

Methods and Protocols. Methods in Molecular Biology 1953

Format: Hardback
Publisher: Humana Press Inc., Totowa, NJ, United States
Published: 26th Mar 2019
Dimensions: w 180mm h 259mm d 29mm
Weight: 785g
ISBN-10: 1493991442
ISBN-13: 9781493991440
Barcode No: 9781493991440
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Synopsis
This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, "big data," and in silico approaches, as well as in vivo applications of CRISPR and best uses of animal models in drug development. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Fully updated and authoritative, Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fields that need a quick overview of these state-of-the-art technologies.

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