Modern Instrumentation Methods and Techniques is a book which aims to discuss the instrumentation methods or techniques which are used for the purpose of analysis. This book includes the classification of instrumentation and fundamental function of the techniques. This book provides the readers with a detailed description about the mass spectrometry and the experimental methods which are used for optical spectroscopy. There are certain surface analysis techniques which are highlighted in this book. The insights of some topics have been provided to the readers in the second half of this book which includes nuclear magnetic resonance spectroscopy, UV/visible spectrophotometry and potentiometric analysis. The book is concluded with certain description about the infrared spectroscopy.