This proceedings book presents papers from the 18th International Scientific Conference, held in September 2019 at Volgograd State University (Russia). The research findings are largely based on the theoretical assumptions of Oleg Inshakov, renowned for his pioneering work on the theory of economic genetics and the theory of "development nucleus" for economic systems. The papers focus on the impact of the 4th industrial revolution on economic growth, the concept of ecosystems corresponding to the rapid spread of digital technologies, regulatory and legal aspects of the Russian economy digitalization, the development of digital technologies in EAEU and BRICS foreign trade, and the corresponding law enforcement measures. The book is intended for academics and practitioners, as well as anyone interested in the problems of new industrialization and the digital transformation of the economy of business entities, regions, countries and integration unions, and their legal regulation to enhance competitiveness on a national and global scale