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Tumor Angiogenesis

A Key Target for Cancer Therapy

Edited by Dieter Marme
Format: Hardback
Publisher: Springer International Publishing AG, Cham, Switzerland
Published: 25th Oct 2018
Dimensions: w 189mm h 285mm d 27mm
Weight: 910g
ISBN-10: 3319336711
ISBN-13: 9783319336718
Barcode No: 9783319336718
This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.

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