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Chromosome Translocation

Advances in Experimental Medicine and Biology 1044

Edited by Yu Zhang
Format: Hardback
Publisher: Springer Verlag, Singapore, Singapore, Singapore
Published: 18th Jul 2018
Dimensions: w 178mm h 254mm
Weight: 3702g
ISBN-10: 9811305927
ISBN-13: 9789811305924
Barcode No: 9789811305924
This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation. It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.

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