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Post-genome Informatics

By (author) Minoru Kanehisa
Format: Paperback / softback
Publisher: Oxford University Press, Oxford, United Kingdom
Published: 1st Apr 2000
Dimensions: w 156mm h 234mm d 9mm
Weight: 235g
ISBN-10: 0198503261
ISBN-13: 9780198503262
Barcode No: 9780198503262
The genome projects have now entered a rapid production phase with complete genome sequences and complete gene catalogues already available for a number of organisms and an increasing number expected shortly. In addition the new DNA and protein chip technologies can produce functional data about genes such as gene expression profiles at a rapid rate. There is therefore a large and ever increasing amount of data about genes and molecules. However there is still a huge gap between information at the molecular level and information at the level of integrated biological systems. It is this gap that is addressed in Post-genome Informatics. Post-genome informatics is the analysis of biological functions in terms of the network of interacting molecules and genes with the aim of understanding how a biological system is organized from its individual building blocks. As well as containing a comprehensive survey of the database and computational technologies relevant to molecular sequence analysis, Post-genome Informatics will provide the reader with a conceptual framework and practical methods for the representation and computation of molecular networks.

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"As a whole the first three chapters would make a valuable basis for tutorial discussions for a final-year graduate students in Bioinformatics." Journal of Cell Science "I would recommend this book to anyone as a very readable and relatively non-technical introduction to computational molecular biology" Statistical Methods in Medical Research